Philadelphia chromosome

常见例句

双语例句

• The Philadelphia chromosome (universally present in CML) is lacking in patients with leukemoid reactions.
  费城染色体（一般出现在CML）在白血病样反应中一般不出现。
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• Philadelphia chromosome formed may result in the generation of the fusion protein BCR ABL, a constitutively activated tyrosine ki nas e which then causes chronic myeloid leukemia (CML).
  慢性粒细胞白血病（CML）患者体内有异常染色体形成并产生BCR ABL融合蛋白，该融合蛋白能激活酪氨酸激酶，刺激细胞过度增生导致慢性粒细胞白血病的发生。

权威例句

• The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
  FORBES: India Court Ruling Against Novartis Is Dark Omen For Big Pharma
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